Pleurodema tucumanum, the spotted-flanks four-eyed frog, is a species of frog in the family Leptodactylidae.
It is endemic to Argentina.

Habitat: This terrestrial frog is found in shrubland between above sea level. It has also been seen in agricultural habitats.

Scientists have reported the frog in protected areas: Parque Nacional Calilegua, Parque Nacional Sierra de las Quijadas, and Parque Provincial Ischigualasto.

Reproduction: This frog is an explosive breeder. The male frogs sit in or near the water and call to the female frogs. The adult frogs make a foam nest for the eggs in pools of water.

Threats: The IUCN classifies this frog as least concern of extinction.