Isotes is a genus of skeletonizing leaf beetles in the family Chrysomelidae. There are currently about 180 described species in Isotes. They are found in the Neotropics.

Species: These 59 species are among those that belong to the genus Isotes:

• Isotes agatha (Bechyné & Bechyné, 1969)
• Isotes albidocincta (Baly, 1889)
• Isotes alcyone (Baly, 1889)
• Isotes antonia (Bechyné, 1956)
• Isotes atriventris (Jacoby, 1880)
• Isotes bertonii (Bowditch, 1912)
• Isotes bicincta (Bowdtich, 1912)
• Isotes blattoides (Jacoby, 1892)
• Isotes borrei (Baly, 1889)
• Isotes brasiliensis (Jacoby, 1888)
• Isotes bruchii
• Isotes cargona (Bechyné, 1958)
• Isotes caryocara (Bechyné, 1956)
• Isotes cinctella (Chevrolat, 1884)
• Isotes complicata (Jacoby, 1887)
• Isotes corallina (Jacoby, 1887)
• Isotes cribrata (Gahan, 1891)
• Isotes crucigera (Weise, 1916)
• Isotes delicula (Erichson, 1847)
• Isotes depressa (Jacoby, 1887)
• Isotes digna (Gahan, 1891)
• Isotes dilatata (Jacoby, 1887)
• Isotes distinguenda (Jacoby, 1887)
• Isotes donata (Bechyné, 1956)
• Isotes eruptiva (Bechyné, 1955)
• Isotes figurata (Jacoby, 1887)
• Isotes gemmula (Jacoby, 1887)
• Isotes ignatia (Bechyné, 1956)
• Isotes imbuta (Erichson, 1847)
• Isotes interruptofasciata (Baly 1879)
• Isotes laevicollis (Jacoby, 1887)
• Isotes lineatopunctata (Jacoby, 1887)
• Isotes marginella (Jacoby, 1879)
• Isotes mexicana (Harold, 1875)
• Isotes multipunctata (Jacoby, 1878)
• Isotes nitidula (Jacoby, 1887)
• Isotes obscuromaculata
• Isotes octosignata (Baly, 1879)
• Isotes onira (Bechyné & Bechyné, 1961)
• Isotes opacicollis
• Isotes pollina (Bechyné & Bechyné, 1962)
• Isotes puella (Baly, 1886)
• Isotes quatuordecimpunctata (Jacoby 1892)
• Isotes rubripennis (Erichson, 1847)
• Isotes sanguineipennis (Baly, 1891)
• Isotes saundersi
• Isotes semiflava (Germar, 1824)
• Isotes semiopaca (Jacoby, 1892)
• Isotes septempunctata (Jacoby, 1887)
• Isotes sexpunctata (Jacoby 1878)
• Isotes sibylla (Bechyné & Bechyné, 1969)
• Isotes spilothorax (Harold, 1875)
• Isotes taeniolata (Gahan, 1891)
• Isotes ternata (Bechyné & Bechyné, 1961)
• Isotes tetraspilota (Baly, 1865)
• Isotes uniformis (Jacoby, 1887)
• Isotes valentina (Bechyné, 1956)
• Isotes varipes (Boheman, 1859)
• Isotes vittula (Bowditch, 1911)